Question: I have eaten omega-3 for 2 weeks, then I went for blood
examination, it appears that the decrease in liver enzymes. I suspected that the
result associated with omega-3 or not?
Answer: Omega-3 means omega-3-polyunsaturated fatty acid (PUFA). Study on effects of omega-3 to the liver did not result in the same direction.
However,
there are studies from systematic literature review and meta-analysis that collecting
the result of studies about patients with non alcoholic fatty liver that often
occurs in people with overweight and insulin resistance.
It
found that PUFA can reduce the amount of liver fat and can reduce liver enzyme
named AST (aspartate aminotransferase) significantly, and PUFA is likely to
reduce the liver enzyme named ALT (alanine aminotransferase) but not clinically
significant.
However
we still do not know the accurate dose of PUFA for decreasing fat or reducing
levels of liver enzymes.
The
study did not gather information from randomized controlled trials. So the result
of study is not enough reliability and may need more support, information, education
in the future. Thus, from the results of the study now it may be possible that
PUFA are useful in reducing fat in the liver and reducing liver enzymes (AST) in
patients with non alcoholic fatty liver
References:
Parker
HM, Johnson NA, Burdon CA , Cohn JS, O'Connor HT, GeorgeJ. Omega-3 supplementation
and non-alcoholic fatty liver disease: a systematic review and meta-analysis. J
Hepatol 2012; 56 (4): 944-51.
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