What is guideline for using MgSo4 to treatment of acute asthma?

Question: I suspect that bringing MgSo4 (50%) used alternately with Berodual NB in the treatment of asthma.

I do not know the guidelines used. And it is effective or not.

Answer: As recommended by the Global initiative for Asthma (GINA) guideline 2014 (the guidelines of the International), found that the use of magnesium sulfate (MgSO4) nebulizer for asthma treatment, not recommended as the initial treatment of acute asthma attack, because there is no difference from the standard treatment. But MgSo4 can be used as additional treatment in patients with acute severe asthma attack, if the standard method has low response to treatment. In these patients showed that adding MgSO4 (nebulizer) can increase FEV1%, O2 saturation and can decrease rate of going to hospital.
Reference: 1. The Global Strategy for Asthma Management and Prevention, Global Initiative for Asthma (GINA) 2014. Available from: http://www.ginasthma.org 
2. Blitz, M, Blitz S, Hughes R, Diner B, Beasley R, et al. Aerosolized magnesium sulfate for acute asthma: a systematic review. Chest 2005;128:337-44
3. Gallegos-Solorzano MC, Pérez-Padilla R, Hernández-Zenteno RJ. Usefulness of inhaled magnesium sulfate in the coadjuvant management of severe asthma crisis in an emergency department. Pulm Pharmacol Ther 2010;23:432-7.