Question: When do we take
allopurinol and colchicine in gout?
Answer: Colchicine is
used for the treatment of acute gout attack by reducing pain and inflammation. The
mechanism of action is unknown. It is believed that the drug involved in the
reaction of the body to respond to the crystals of uric acid. The drug is used
only for short periods and stopped when the pain relief. This drug does not
slow the progress of gout.
Allopurinol is the drug that reduces uric acid levels
in the blood. It inhibits xanthine oxidase which is enzyme in the process of producing
uric acid. The Drug used in patients with high blood levels of uric acid, but no
effective treatment for acute gout attack.
Reference:
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