Question: Eritromax can be
used instead of Hemaplus or not.
Answer: Generic name of Eritromax®
and Hemaplus® are similar; alpha erythropoietin. They are a type of biological
drugs that contain glycosylated protein.
Each brand of drug has a different manufacturing
process. Each drug affects each patient differently in terms of effectiveness
and safety, especially the ability to producing an immune response (immunogenicity),
and adverse reaction of drug is pure red cell aplasia (bone marrow does not
build red blood cells permanently). This results in severe fatal of the
patient.
Therefore, the use of alpha erythropoietin, not
recommended changing brands of drug, because it affects the efficiency of treatment
and affects the patient safety.
References:
1. Ping NH, Lim C, Francisco JC, Peria AL,
Fajayan JL, Sollvet JZ, et al. Mims Thailand. 133rd ed. Bangkok, 2013.
2. Praditpornsilpa K, Tiranathanagul K,
Kupatawintu P, Jootar S, Intragumtornchai T, Tungsanga K, et al. Bio¬similar
recombinant human erythropoietin induces the production of neutralizing
antibodies. Kidney Int 2011; 80 (1): 88-92.
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